Chapter 1424: Chapter 1067: Of the Weak Water Three Thousand, I Scoop Only One Ladleful_2 Chapter 1424: Chapter 1067: Of the Weak Water Three Thousand, I Scoop Only One Ladleful_2 The fever lasted longer this time than before, but fortunately, it fluctuated around 39.0 degrees and never exceeded 40 degrees, with the lowest being about 38.5 degrees. Its fever pattern was wave-like, which is consistent with the K virus’s struggle with the immune system inside the body, because the current K virus is completely different from the previous one. The previous K virus had its replication gene knocked out; it was a castrated virus that would continuously decrease in number under the attack of the immune system, so once the high fever passed its peak, it could only decline thereafter.

The current K virus has the ability to replicate. When the human immune system kills part of the virus, it can recover its numbers through replication, presenting a tug-of-war with the human immune system. This tug-of-war is reflected in the wave-like pattern of the fever.

The biopsy samples of the living tumor tissue sent for examination indeed confirmed Professor Yang’s prediction. Unlike the previous trials, this time, a very large proportion of tumor cells were infected by the experimental virus. Observations from the biopsied tumor cell samples showed that over 10% of the tumor cells were infected, and this ratio is still increasing as the virus replicates. Samples taken from different areas showed great uniformity.

Due to the dangerous nature of intracranial tumors, they could not be biopsied for samples. However, from the infection rate in tissue samples taken from other tumor sites, it’s almost certain that the intracranial tumors are likely infected with the virus, as the modified virus is able to penetrate the blood-brain barrier.

This result made Liang Ping extremely excited. After surviving the attack from the body’s immune system, a portion of the K virus successfully reached the tumor cells, where it began to use the tumor’s nutrients to replicate.

It was unexpected that such a cautious risk would bring such a great reward. It seems that playing it safe is not always the best option. Innovation requires a spirit of risk-taking.

As observations continued, the infected tumor cells began to undergo apoptosis en masse. Calculations showed that nearly 3% of the tumor was dying off. The infection and apoptosis ratios maintained a three-to-one ratio as before. Due to the increased infection rate, the apoptosis rate also increased correspondingly.

A 3% apoptosis rate – what does that mean? It certainly exceeds the growth rate of the tumor. If treatments continue in this way, there is hope for curing the tumor. It was unexpected that switching from a strict virus to a live virus treatment would bring such good effects.

At this stage of the experiment, Professor Yang began to think about naming this K virus. After numerous modifications, it couldn’t be called a virus anymore. It needed a brand new name – Undifferentiated Cell-Targeted Apoptotic Protein Complex Factor. Professor Yang wrote this well-thought-out name on the whiteboard in his office.

Looking at this impressive name, Professor Yang leaned back in his chair in his office to rest. He hadn’t returned home these days; it was time to go back and hug his son. Of course, he also needed to hug his wife.

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Every examination of Sisi’s heart showed improvement over the previous one, indicating that the tumor was continuing to shrink. The improvement in cardiac function suggested that the impact of the intracranial tumor on the brain stem was decreasing. Such visible changes were more reliable than experimental data. After all, in clinical medicine, any data must be translated into clinical changes to have practical significance.

After the virus injection, apart from a few days of fever, no other adverse symptoms appeared, boosting the confidence of the experimental team once again.

Recalling the beginning of the experiment, the team had stumbled through, and now everything was under control, there was an undeniable sense of amazement in everyone’s hearts. Professor Yang was remarkable; his brain was like that of an alien.

The K factor, the recombinant adenovirus, the combination of the two, going directly to clinical trials, using a replicable virus for experimentation, and classifying this virus as a replicable protein complex capable of initiating the apoptosis program in tumor cells without the K factor – each of these was an astonishing and incredible innovation.

His experiment seemed rough at the start, entirely like a fantasy, feeling too whimsical. At that time, even the researchers at Nandu Medical University Virus Laboratory privately discussed that such an idea was impossible to realize, way too fanciful.

But as the experiment progressed, it became increasingly clearer and more likely to succeed, ultimately achieving success. The entire process seemed a bit incredible.

Moreover, Yang Ping’s calm and rational response to failure also surprised them, because most people would be somewhat affected by failure, but he was not fazed at all. Even after a setback, he remained filled with passion, as if he had already determined that he would be successful.

Yang Ping himself did not know why he had such a talent to always maintain a strong passion and curiosity. He had an accurate grasp of the research direction by relying on intuition combined with logic, which might be the result of his previous devil-style training in the System Space.

When Sisi’s next MRI images came out, Yang Ping measured the tumor volume, especially the intracranial tumors. They had not only stopped growing, but also shrank compared to before, albeit very slightly. Yet, the extent of reduction had increased significantly compared to the previous measurements.

The data matched the clinical symptoms, and now the subsequent experiments could be carried out unimpeded. As for ethical issues, there’s also the logic of “victorious kings and defeated bandits.” When you fail, you invite countless accusations. When you succeed, others only see your results and forget the process.

During his rounds, Yang Ping paid special attention to the cactus in the corner. It was getting greener and more robust, and Sisi’s spirits had improved as well.

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Fujiwara Masao had some previous acquaintance with Director Han. He wrote a letter to Director Han hoping to help arrange for Fujiwara Miyuki to come to China for an extended period of training, about three years.

Miyuki had a good impression from her previous short-term training here, so now she wanted a longer period of training, hoping to learn from Professor Yang’s superb medical skills, and later contribute to the health of Japanese people.

After reading the letter, Director Han pondered. Whether it was Chinese proficiency or other aspects, Fujiwara Miyuki met the criteria, and international exchanges for training are normal.

But now, Director Han was not very familiar with Yang Ping’s situation. Yang Ping was already an independent leader of an institute’s discipline. His current work was just to provide logistics support. Director Han informed Yang Ping about the matter to let him decide.

Yang Ping thought about it. At this time, whether it was domestic or international, those who came for training had to be treated with caution. He passed the matter to Manager Qiu.

Manager Qiu is currently responsible for all the security work surrounding Yang Ping. He was highly vigilant about Fujiwara Miyuki’s visit, feeling it might be related to Yang Ping’s latest research findings. Huang Jiachai had already informed him of the importance of Professor Yang’s research findings, which could potentially shake the foundations of many pharmaceutical giants. These people would either try to attract Yang Ping or exhaust all means to steal the research findings. If neither of the first two was possible, they might take risks and resort to extreme measures to stop Yang Ping’s research progress. When capital gets bloodthirsty, anything is possible. Manager Qiu immediately reported the matter to his superiors, and the superiors replied: She can come, but we must make good use of her to get a hold of the opponent’s arrangements quickly.

Before coming, Fujiwara Miyuki contacted Xiao Su and Tang Fei. When she was training in China, the three of them had a good relationship, considered sisters, and had traveled together to Hangzhou. This return was to give her sisters a heads-up.

As for Miyuki’s return, Yang Ping had no ripples in his heart. His thoughts on matters of men and women were simple–he would only take a single ladle from the “endless waters.” He now had a wife and children; he could not afford to make a mistake in this regard.

So whether she came or not, Yang Ping didn’t have many thoughts. Whether to agree to her coming or not, he left the decision to Manager Qiu.